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Compounds
Peptides

Humanin Peptide: Dosing Protocols

Humanin, a mitochondrial-derived peptide, has gained interest among researchers for its potential benefits in mitochondrial health and longevity.

01

Dosage Range

  • A theoretical dosage of 25-50 μg daily has been suggested (anecdotal).
  • One user reported using 5 mg once per week.
02

Humanin vs. Humanin G

  • Humanin G is a variant reported to be more potent than standard Humanin.
03

Frequency of Administration

  • One anecdotal user reported administering 5 mg once per week, on Wednesdays.
04

Stability Concerns

  • Stability of Humanin in solution is a concern.
  • Humanin has a short half-life.
  • Syringe filters have been suggested to help maintain sterility when dividing doses.
05

Combination with Other Peptides

  • The same user paired Humanin with MOTS-C taken on Mondays and Fridays.
  • A reported "Fitness Protocol" combines NAD, MOTS-C, and Humanin, administered subcutaneously (SubQ) 5 of 7 days in the morning (AM).
06

Safety Considerations

  • A potential safety concern is STAT3 activation.
  • The short half-life may help mitigate this risk.
  • Long-term safety data is lacking.
07

The Bottom Line

  • These are not scientifically validated protocols.
  • The optimal dosage, timing, and duration for human use remain unknown.
References
  1. 01Reddit — Humanin stability: https://www.reddit.com/r/Peptides/comments/j8qqvo/humanin_stability/
  2. 02Reddit — Humanin G: https://www.reddit.com/r/Peptides/comments/11qzuj9/curious_about_humanin_and_wondering_about/
  3. 03Reddit — Humanin experiences: https://www.reddit.com/r/Peptides/comments/1bohgiw/humanin_experiences/
  4. 04Reddit — Fitness Protocol: https://www.reddit.com/r/DecentralizedSci/comments/18iift7/what_is_your_favorite_peptide_protocol/

This profile is being expanded — additional sections from the source are still being added.

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